BDBM513950 1-((5-Chloro-2-((8-(((1,1,1,3,3,3- hexafluoropropan-2-yl)oxy)carbonyl)-1,8- diazaspiro[4.5]decan-1- yl)methyl)phenoxy)methyl)cyclopropane-1- carboxylic acid::US11059822, Example 20::US11691975, Example 20

SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2ccc(Cl)cc2OCC2(CC2)OC=O)CC1)C(F)(F)F

InChI Key InChIKey=ZDKYYZONTNROOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 513950   

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM513950(1-((5-Chloro-2-((8-(((1,1,1,3,3,3- hexafluoropropa...)
Affinity DataIC50: 550nMAssay Description:Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0-2.0 mg/mL total protein concentration) were preincubated with varying...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
Go to US Patent

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM513950(1-((5-Chloro-2-((8-(((1,1,1,3,3,3- hexafluoropropa...)
Affinity DataIC50: 550nMAssay Description:Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0-2.0 mg/mL total protein concentration) were preincubated with varying...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
Go to US Patent