BDBM513996 (2S)-1-((4R,7S)-7-((2R,3S,4R,11 S,12R)-12-benzyl-3,11-dihydroxy-4-methyltetradecan-2-yl)-2-hydroxy-4-methyl-3-oxooxepane-2-carbonyl)piperidine-2-carboxylic acid C-11 lactone::US11059830, Compound 6

SMILES CC[C@H](Cc1ccccc1)[C@@H]1CCCCCC[C@@H](C)[C@H](O)[C@@H](C)[C@@H]2CC[C@@H](C)C(=O)C(O)(O2)C(=O)N2CCCC[C@H]2C(=O)O1

InChI Key InChIKey=QHIRTSSRGUQDAS-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 513996   

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Revolution Medicines

US Patent
LigandPNGBDBM513996((2S)-1-((4R,7S)-7-((2R,3S,4R,11 S,12R)-12-benzyl-3...)
Affinity DataKd:  0.510nMAssay Description:The binding of compounds of the invention to FKBP12 can be determined using the following protocol.General ProtocolThis protocol utilizes Perkin Elme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Revolution Medicines

US Patent
LigandPNGBDBM513996((2S)-1-((4R,7S)-7-((2R,3S,4R,11 S,12R)-12-benzyl-3...)
Affinity DataKd:  21.5nMAssay Description:This protocol utilizes Surface Plasmon Resonance (SPR) as a method to determine kinetics (KD, Ka, Kd) for the binding of compound (analyte) to immobi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent