BDBM514233 The Preparation of (+-)(Z)-N-(3-bromo-4-fluorophenyl)-N′-hydroxy-4-((2-(thio-methyl sulfoxide cyanoimine)ethyl)amino)-1,2,5-oxadiazole-3-carboxamidine ::US11053207, Compound 6::US11053207, Compound 6A::US11053207, Compound 6B

SMILES CS(=O)(CCNc1nonc1\C(Nc1ccc(F)c(Br)c1)=N\O)=NC#N

InChI Key InChIKey=GGHPYZYCOWLIBW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 514233   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514233(US11053207, Compound 6A | The Preparation of (+-)(...)
Affinity DataIC50: 11nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514233(US11053207, Compound 6A | The Preparation of (+-)(...)
Affinity DataIC50: 82nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514233(US11053207, Compound 6A | The Preparation of (+-)(...)
Affinity DataIC50: 88nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent