BDBM514601 US11098029, Example 37

SMILES COc1ccc(CN([C@H]2C[C@@H](C)N([C@H]2CO[C@H]2CC[C@H](CC2)c2cccc(F)c2)C(=O)OCc2ccccc2)S(=O)(=O)N(C)C)cc1

InChI Key InChIKey=NENBOFYUTXEUCQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 514601   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM514601(US11098029, Example 37)
Affinity DataIC50: 0.230nMAssay Description:In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM514601(US11098029, Example 37)
Affinity DataIC50: 1.03E+3nMAssay Description:In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent