BDBM516364 US11053241, Compound I-90

SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1c(F)cc(cc1N1CC[C@H](C1)OC)-c1nccn1C

InChI Key InChIKey=LFRAQFBPBXCHJB-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 516364   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM516364(US11053241, Compound I-90)
Affinity DataKd: <0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent