BDBM516377 (2S)-1-(phenylacetyl)- N-{2-[4-({[(2S)-1- (phenylacetyl)pyrrolidin-2- yl]carbonyl}amino)phenyl]- 1H-pyrrolo[3,2-b]pyridin-5- yl}pyrrolidine-2-carboxamide::US11053243, Example 2

SMILES O=C(Cc1ccccc1)N1CCC[C@H]1C(=O)Nc1ccc(cc1)-c1cc2nc(NC(=O)[C@@H]3CCCN3C(=O)Cc3ccccc3)ccc2[nH]1

InChI Key InChIKey=ZWGFJQBNRCTGIS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 516377   

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516377(US11053243, Example 2 | (2S)-1-(phenylacetyl)- N-{...)
Affinity DataEC50:  9nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent