BDBM516551 (2S)-1-[(2R)-2-(dimethylamino)- 2-phenylacetyl]-N-(2-{4-[({(2S)- 1-[(2R)-tetrahydrofuran-2- ylcarbonyl]pyrrolidin-2- yl}carbonyl)amino]phenyl}-1H- indol-5-y])pyrrolidine-2- carboxamide::US11053243, Example 72

SMILES CN[C@@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc2[nH]c(cc2c1)-c1ccc(NC(=O)[C@@H]2CCCN2C(=O)[C@H]2CCCO2)cc1)c1ccccc1

InChI Key InChIKey=PYVONQUECYNVEN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 516551   

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516551(US11053243, Example 72 | (2S)-1-[(2R)-2-(dimethyla...)
Affinity DataEC50:  0.170nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent