BDBM516561 US11053243, Example 107::tert-butyl {(1R)-2-[(2S)-2-({2- [4-(2-{(2S)-1-[(2R)-2- (dimethylamino)-2- phenylacetyl]pyrrolidin-2-yl}- 1H-imidazol-5-yl)phenyl]-1H- indol-5-yl}carbamoyl)pyrrolidin- 1-yl]-2-oxo-1- phenylethyl}carbamate

SMILES CN(C)[C@@H](C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1cc2cc(NC(=O)[C@@H]3CCCN3C(=O)[C@H](NC(=O)OC(C)(C)C)c3ccccc3)ccc2[nH]1)c1ccccc1

InChI Key InChIKey=AJYSXMGBBDTTAW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 516561   

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516561(US11053243, Example 107 | tert-butyl {(1R)-2-[(2S)...)
Affinity DataEC50:  0.0400nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent