BDBM516571 (2S) N-{4-[3-cyano-5-({[(2S)-1-(phenylacetyl)pyrrolidin-2-yl]carbonyl}amino)-1H-indol-2-yl]phenyl}-1-(phenylacetyl)pyrrolidine-2-carboxamide::US11053243, Example 155

SMILES Brc1c([nH]c2ccc(NC(=O)[C@@H]3CCCN3C(=O)Cc3ccccc3)cc12)-c1ccc(NC(=O)[C@@H]2CCCN2C(=O)Cc2ccccc2)cc1

InChI Key InChIKey=AEDOURZAJMSKMP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 516571   

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516571((2S) N-{4-[3-cyano-5-({[(2S)-1-(phenylacetyl)pyrro...)
Affinity DataEC50:  0.900nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
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Date in BDB:
2/13/2022
Entry Details
US Patent