BDBM516576 US11053243, Example 186::tert-butyl {(1S)-2-[(2S)-2-{[4-(5- cyano-1H-indol-2-yl)phenyl] carbamoyl}pyrrolidin-1-yl]-2- oxo-1-phenylethyl}carbamate

SMILES CC(C)(C)OC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc(cc1)-c1cc2cc(ccc2[nH]1)C#N)c1ccccc1

InChI Key InChIKey=XTZCHOMMYCPWKW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 516576   

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516576(US11053243, Example 186 | tert-butyl {(1S)-2-[(2S)...)
Affinity DataEC50:  0.0150nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent