BDBM516931 US11104675, Example 17

SMILES Cc3nc(N1CCC2(CC1)CO[C@@H](C)[C@H]2N)c(Cl)c(=O)n3c4ccnc(Cl)c4Cl

InChI Key InChIKey=FTEPHBNKOOSIFX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 516931   

LigandPNGBDBM516931(US11104675, Example 17)
Affinity DataIC50: 618nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent