BDBM517140 5-[(4-methoxyphenyl)methyl]-6- (oxetan-3-ylmethyl)-1- tetrahydropyran-4-yl-pyrazolo[3,4- d]pyrimidin-4-one::US11104680, Example 9

SMILES COc1ccc(Cn2c(CC3COC3)nc3n(ncc3c2=O)C2CCOCC2)cc1

InChI Key InChIKey=MWPSAGRFLKLXIM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 517140   

LigandPNGBDBM517140(US11104680, Example 9 | 5-[(4-methoxyphenyl)methyl...)
Affinity DataIC50: 58nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandPNGBDBM517140(US11104680, Example 9 | 5-[(4-methoxyphenyl)methyl...)
Affinity DataIC50: 165nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent