BDBM517166 5-(4-methoxybenzyl)-6-methyl-1-(4- methyltetrahydro-2H-pyran-4-yl)-1,5- dihydro-4H-pyrazolo[4,3-c]pyridin-4- one::US11104680, Example 29

SMILES COc1ccc(Cn2c(C)cc3n(ncc3c2=O)C2(C)CCOCC2)cc1

InChI Key InChIKey=VWDZYEFJJSYZME-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 517166   

LigandPNGBDBM517166(US11104680, Example 29 | 5-(4-methoxybenzyl)-6-met...)
Affinity DataIC50: 87nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandPNGBDBM517166(US11104680, Example 29 | 5-(4-methoxybenzyl)-6-met...)
Affinity DataIC50: 119nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandPNGBDBM517166(US11104680, Example 29 | 5-(4-methoxybenzyl)-6-met...)
Affinity DataIC50: 174nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent