BDBM517262 3-(2-chlorophenyl)-1-(4- fluorophenyl)-N-[1- (hydroxymethyl)cyclobutyl]-1H- indazole-6-carboxamide::US11104690, Example 88

SMILES OCC1(CCC1)NC(=O)c1ccc2c(nn(-c3ccc(F)cc3)c2c1)-c1ccccc1Cl

InChI Key InChIKey=KFRZELCFLDVTGY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517262   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM517262(US11104690, Example 88 | 3-(2-chlorophenyl)-1-(4- ...)
Affinity DataIC50: 15nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent