BDBM517863 2-[(2R)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxy-propyl]-7-(trifluoromethoxy)-4,5- dihydro-3H-2-benzazepin-1-one::US11111237, Example 6::US11725001, Example 6

SMILES O[C@H](CN1CCc2ccccc2C1)CN1CCCc2cc(OC(F)(F)F)ccc2C1=O

InChI Key InChIKey=CDTUGJDWBKTIKH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 517863   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM517863(US11111237, Example 6 | 2-[(2R)-3-(3,4-dihydro-1H-...)
Affinity DataIC50: 50nMAssay Description:The histone H4 peptide was diluted with carbonate-bicarbonate buffer and prepared to 100 μg/mL, and then dispensed onto the plate per 100 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2023
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM517863(US11111237, Example 6 | 2-[(2R)-3-(3,4-dihydro-1H-...)
Affinity DataIC50: 50nMAssay Description:Experimental procedure: The histone H4 peptide was diluted with carbonate-bicarbonate buffer and prepared to 100 μg/mL, and then dispensed onto ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent