BDBM5180 6-chloro-7-phenyl-2H-[1,3]dioxolo[4,5-g]quinoline::Quinoline-Containing Inhibitor 14

SMILES Clc1nc2cc3OCOc3cc2cc1-c1ccccc1

InChI Key InChIKey=TWSDEOXKXYWQFW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5180   

TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

LigandPNGBDBM5180(6-chloro-7-phenyl-2H-[1,3]dioxolo[4,5-g]quinoline ...)
Affinity DataIC50: 3.00E+4nMpH: 7.5 T: 2°CAssay Description:The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Hebrew University of Jerusalem

LigandPNGBDBM5180(6-chloro-7-phenyl-2H-[1,3]dioxolo[4,5-g]quinoline ...)
Affinity DataIC50: 3.00E+4nMAssay Description:The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2005
Entry Details Article
PubMed