BDBM518142 US11111240, Example 19

SMILES Fc1cccc(c1)N(C(C(=O)NC1CCCCC1)c1ccccc1Cl)C(=O)[C@@H]1CCS(=O)(=O)N1c1cc(ccn1)C#C

InChI Key InChIKey=AXYMXNPWOMUALJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518142   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Chai Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM518142(US11111240, Example 19)
Affinity DataIC50: 1.00E+3nMAssay Description:The specific operation was as follows: 2.5 μl of the compound diluted in a 3-fold gradient was added to a 384-well plate, followed by adding 5 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent