BDBM518148 US11111240, Example 25

SMILES CN1C[C@H](N(c2cc(ccn2)C#N)S1(=O)=O)C(=O)N(C(C(=O)NC1CC(F)(F)C1)c1ccccc1Cl)c1cccc(F)c1

InChI Key InChIKey=ORUVRAVGPWHFEU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518148   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Chai Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM518148(US11111240, Example 25)
Affinity DataIC50: 20nMAssay Description:The specific operation was as follows: 2.5 μl of the compound diluted in a 3-fold gradient was added to a 384-well plate, followed by adding 5 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent