BDBM518197 US11111247, Example 27

SMILES COC(=O)N1C[C@H](C)N([C@H](C)C1)c1ncc2[nH]nc(-c3ccc(cc3)C3CCN(C)C3)c2n1

InChI Key InChIKey=HXUSWYFYCFZUIX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 518197   

TargetActivin receptor type-1 [147-509](Human)
Incyte

US Patent
LigandPNGBDBM518197(US11111247, Example 27)
Affinity DataIC50: 100nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetActivin receptor type-1 [147-509](Human)
Incyte

US Patent
LigandPNGBDBM518197(US11111247, Example 27)
Affinity DataIC50: 300nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent