BDBM518250 US11111247, Example 73

SMILES CN1CC2CCC(N2c2ncc3[nH]nc(-c4cnn(c4)-c4cncc(c4)C#N)c3n2)C1=O

InChI Key InChIKey=LZEBBGQFZXWKCV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 518250   

TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM518250(US11111247, Example 73)
Affinity DataIC50: 100nMAssay Description:un-Phosphorylated (UP): The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM518250(US11111247, Example 73)
Affinity DataIC50: 100nMAssay Description:Phosphorylated (P): The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM518250(US11111247, Example 73)
Affinity DataIC50: 300nMAssay Description:un-Phosphorylated (UP): The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent