BDBM518395 1-[6-(4-Isopropyl-1,2,4-triazol-3-yl)-2-pyridyl]-3-[2-(3-pyridyl)ethyl]imidazolidin-2-one::US11124496, Example 1

SMILES CC(C)n1cnnc1-c1cccc(n1)N1CCN(CCc2cccnc2)C1=O

InChI Key InChIKey=OJINOEBKCFMWGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518395   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Eli Lilly

US Patent
LigandPNGBDBM518395(US11124496, Example 1 | 1-[6-(4-Isopropyl-1,2,4-tr...)
Affinity DataIC50: 36nMAssay Description:The purpose of this assay is to determine the effect of ASK1 inhibitors on the production of ADP by ASK1. The recombinant human ASK1 (hASK1) catalyti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent