BDBM5184 2,3-Diphenyl-6,7-dimethoxyquinoline::6,7-dimethoxy-2,3-diphenylquinoline::Quinoline-Containing Inhibitor 18

SMILES COc1cc2cc(-c3ccccc3)c(nc2cc1OC)-c1ccccc1

InChI Key InChIKey=MRAWBMVCIHFKSI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5184   

TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

LigandPNGBDBM5184(6,7-dimethoxy-2,3-diphenylquinoline | 2,3-Diphenyl...)
Affinity DataIC50: 3.00E+4nMpH: 7.5 T: 2°CAssay Description:The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Hebrew University of Jerusalem

LigandPNGBDBM5184(6,7-dimethoxy-2,3-diphenylquinoline | 2,3-Diphenyl...)
Affinity DataIC50: 3.00E+4nMAssay Description:The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2005
Entry Details Article
PubMed