BDBM518401 1-[2-(4-Cyclopropylimidazol-1-yl)ethyl]-3-[6-(4-isopropyl-1,2,4-triazol-3-yl)-2-pyridyl]imidazolidin-2-one::US11124496, Example 3

SMILES CC(C)n1cnnc1-c1cccc(n1)N1CCN(CCn2cnc(c2)C2CC2)C1=O

InChI Key InChIKey=BKNDPKKBOUGUGU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518401   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Eli Lilly

US Patent
LigandPNGBDBM518401(US11124496, Example 3 | 1-[2-(4-Cyclopropylimidazo...)
Affinity DataIC50: 10.8nMAssay Description:The purpose of this assay is to determine the effect of ASK1 inhibitors on the production of ADP by ASK1. The recombinant human ASK1 (hASK1) catalyti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent