BDBM518403 1-(6-(4-Isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)imidazolidin-2-one::US11124496, Example 5

SMILES CC(C)n1cnnc1-c1cccc(n1)N1CCNC1=O

InChI Key InChIKey=ZGBDDSAMPFBDCF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518403   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Eli Lilly

US Patent
LigandPNGBDBM518403(US11124496, Example 5 | 1-(6-(4-Isopropyl-4H-1,2,4...)
Affinity DataIC50: 64.4nMAssay Description:The purpose of this assay is to determine the effect of ASK1 inhibitors on the production of ADP by ASK1. The recombinant human ASK1 (hASK1) catalyti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent