BDBM518476 US11124509, Compound 48

SMILES CC(C)n1ccc(n1)-c1nc(CNc2ccc(F)c(F)c2)[nH]c1-c1ccc2nccnc2c1

InChI Key InChIKey=JKWGZCPQUGCTMR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518476   

TargetTGF-beta receptor type-1(Human)
Clavius Pharmaceuticals

US Patent
LigandPNGBDBM518476(US11124509, Compound 48)
Affinity DataIC50: 100nMAssay Description:Exemplified compounds were screened in 1% DMSO (final concentration) by 3-fold serial dilutions from 10,000 nM to 0.316 nM to produce an IC50 or at s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent