BDBM5185 (2-(p-Nitrophenyl)-3-carbomethoxy-6,7-dimethoxyquinoline)::Quinoline-Containing Inhibitor 19::methyl 6,7-dimethoxy-2-(4-nitrophenyl)quinoline-3-carboxylate

SMILES COC(=O)c1cc2cc(OC)c(OC)cc2nc1-c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=ZHROVCLRKOLMGN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5185   

TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

LigandPNGBDBM5185((2-(p-Nitrophenyl)-3-carbomethoxy-6,7-dimethoxyqui...)
Affinity DataIC50: 3.00E+4nMpH: 7.5 T: 2°CAssay Description:The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Hebrew University of Jerusalem

LigandPNGBDBM5185((2-(p-Nitrophenyl)-3-carbomethoxy-6,7-dimethoxyqui...)
Affinity DataIC50: 3.00E+4nMAssay Description:The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2005
Entry Details Article
PubMed