BDBM518541 2-Allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-((2-(oxetan-3-yl)-1,2,3,4-tetrahydroisoquinolin-6-yl)amino)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one::US11124518, Example 18

SMILES CC(C)(O)c1cccc(n1)-n1n(CC=C)c(=O)c2cnc(Nc3ccc4CN(CCc4c3)C3COC3)nc12

InChI Key InChIKey=XRLVZQOAYKJPKT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518541   

TargetWee1-like protein kinase(Human)
Recurium Ip Holdings

US Patent
LigandPNGBDBM518541(US11124518, Example 18 | 2-Allyl-1-(6-(2-hydroxypr...)
Affinity DataIC50: 10nMAssay Description:Wee 1 kinase was determined by using Flurorescence Resonance Energy Transfer (FRET) assay. In 384-well plates, Wee1 kinase (2 nM final concentration)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent