BDBM518704 4-(ethylamino)-6- ((2-methoxy-4- (morpholine-4- carbonyl)phenyl) amino)-1H- pyrrolo[2,3- b]pyridine-3- carbonitrile::US11117892, Example 2

SMILES CCNc1cc(Nc2ccc(cc2OC)C(=O)N2CCOCC2)nc2[nH]cc(C#N)c12

InChI Key InChIKey=NDGBSOONSFYVIW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 518704   

LigandPNGBDBM518704(US11117892, Example 2 | 4-(ethylamino)-6- ((2-meth...)
Affinity DataIC50: 10nMAssay Description:Table 5: Particularly, a substrate was added to a basic reaction buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandPNGBDBM518704(US11117892, Example 2 | 4-(ethylamino)-6- ((2-meth...)
Affinity DataIC50: 10nMAssay Description:Table 6: LanthaScreen Eu-anti-GST Antibody (Invitrogen, PV5594) and DYRK1A (Invitrogen, PV3785) were diluted to make the final concentrations of 6 nM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent