BDBM518721 N4-ethyl-N6-(1- methyl-1H- pyrazol-3-yl)-3- (trifluoromethyl)- 1H-pyrrolo[2,3- b]pyridine-4,6- diamine::US11117892, Example 54

SMILES CCNc1cc(Nc2ccn(C)n2)nc2[nH]cc(c12)C(F)(F)F

InChI Key InChIKey=RKGMNIVNCSSXKQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518721   

LigandPNGBDBM518721(US11117892, Example 54 | N4-ethyl-N6-(1- methyl-1H...)
Affinity DataIC50: 100nMAssay Description:Table 5: Particularly, a substrate was added to a basic reaction buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, ...More data for this Ligand-Target Pair
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Date in BDB:
2/26/2022
Entry Details
US Patent