BDBM518749 (R)-(2,4- dimethylpiperazin- 1-yl)(2-fluoro- 5-methoxy-4-((4- (methylamino)-3- (trifluoromethyl)- 1H-pyrrolo[2,3- b]pyridin-6- yl)amino)phenyl) methanone::US11117892, Example 75

SMILES CNc1cc(Nc2cc(F)c(cc2OC)C(=O)N2CCN(C)C[C@H]2C)nc2[nH]cc(c12)C(F)(F)F

InChI Key InChIKey=YTGXYDBURDKPFH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518749   

LigandPNGBDBM518749(US11117892, Example 75 | (R)-(2,4- dimethylpiperaz...)
Affinity DataIC50: 100nMAssay Description:Table 5: Particularly, a substrate was added to a basic reaction buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, ...More data for this Ligand-Target Pair
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Date in BDB:
2/26/2022
Entry Details
US Patent