BDBM518770 (3-methoxy-4-((4- methoxyethyl) (methyl)amino)-3- (trifluoromethyl)- 1H-pyrrolo[2,3- b]pyridin-6-yl) amino)phenyl)((4- morpholino- piperidin-1-yl) methanone::US11117892, Example 88

SMILES COCCN(C)c1cc(Nc2ccc(cc2OC)C(=O)N2CCC(CC2)N2CCOCC2)nc2[nH]cc(c12)C(F)(F)F

InChI Key InChIKey=AQKYKZCDPKVFHN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518770   

LigandPNGBDBM518770(US11117892, Example 88 | (3-methoxy-4-((4- methoxy...)
Affinity DataIC50: 55nMAssay Description:Table 5: Particularly, a substrate was added to a basic reaction buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent