BDBM518776 (R)-(4-((4-((1- hydroxy-3- methylbutan-2-yl) amino)-3- (trifluoromethyl)- 1H-pyrrolo[2,3- b]amino)-3- methoxyphenyl) (morpholino) methanone::US11117892, Example 92

SMILES COc1cc(ccc1Nc1cc(N[C@@H](CO)C(C)C)c2c(c[nH]c2n1)C(F)(F)F)C(=O)N1CCOCC1

InChI Key InChIKey=XKCFTEHJGCPIJC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518776   

LigandPNGBDBM518776(US11117892, Example 92 | (R)-(4-((4-((1- hydroxy-3...)
Affinity DataIC50: 100nMAssay Description:Table 5: Particularly, a substrate was added to a basic reaction buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, ...More data for this Ligand-Target Pair
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Date in BDB:
2/26/2022
Entry Details
US Patent