BDBM518778 (S)-(4-((4-(2- butylamino)-3- (trifluoromethyl)- 1H-pyrrolo[2,3- b]pyridin-6- yl)amino)-3- methoxyphenyl)(4- morpholino- piperidin-1-yl)- methanone::US11117892, Example 93

SMILES CC[C@H](C)Nc1cc(Nc2ccc(cc2OC)C(=O)N2CCC(CC2)N2CCOCC2)nc2[nH]cc(c12)C(F)(F)F

InChI Key InChIKey=DGNJZUPLEZLZLO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518778   

LigandPNGBDBM518778(US11117892, Example 93 | (S)-(4-((4-(2- butylamino...)
Affinity DataIC50: 100nMAssay Description:Table 5: Particularly, a substrate was added to a basic reaction buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent