BDBM518780 (4-((4- (cyclopropylamino)- 3- (trifluoromethyl)- 1-((2- (trimethylsilyl) ethoxy)methyl)- 1H-pyrrolo[2,3- b]pyridin-6-yl)3- methoxyphenyl) (4- morpholino- piperidine-1- yl)methanone::US11117892, Example 94

SMILES COc1cc(ccc1Nc1cc(NC2CC2)c2c(c[nH]c2n1)C(F)(F)F)C(=O)N1CCC(CC1)N1CCOCC1

InChI Key InChIKey=RBTKOQCREJDPQN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518780   

LigandPNGBDBM518780(US11117892, Example 94 | (4-((4- (cyclopropylamino...)
Affinity DataIC50: 55nMAssay Description:Table 5: Particularly, a substrate was added to a basic reaction buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent