BDBM518840 (2-fluoro-5- methoxy-4-((4- (methylamino)-3- (trifluoromethyl)- 1H-pyrrolo[2,3- b]pyridin-6- yl)amino)phenyl) (4- methylpiperazin- 1-yl)methanone::US11117892, Example 60

SMILES CNc1cc(Nc2cc(F)c(cc2OC)C(=O)N2CCN(C)CC2)nc2[nH]cc(c12)C(F)(F)F

InChI Key InChIKey=MANOVQANPCRIJU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518840   

LigandPNGBDBM518840(US11117892, Example 60 | (2-fluoro-5- methoxy-4-((...)
Affinity DataIC50: 55nMAssay Description:Table 6: LanthaScreen Eu-anti-GST Antibody (Invitrogen, PV5594) and DYRK1A (Invitrogen, PV3785) were diluted to make the final concentrations of 6 nM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent