BDBM518841 (3-methoxy-4-((4- (methylamino)-3- (trifluoromethyl)- 1H-pyrrolo[2,3- b]pyridin-6- yl)amino)phenyl) (4-(4- methylpiperazin- 1-yl)piperidin-1- yl)methanone::US11117892, Example 61

SMILES CNc1cc(Nc2ccc(cc2OC)C(=O)N2CCC(CC2)N2CCN(C)CC2)nc2[nH]cc(c12)C(F)(F)F

InChI Key InChIKey=BWAALJOLIGSLTF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518841   

LigandPNGBDBM518841(US11117892, Example 61 | (3-methoxy-4-((4- (methyl...)
Affinity DataIC50: 10nMAssay Description:Table 6: LanthaScreen Eu-anti-GST Antibody (Invitrogen, PV5594) and DYRK1A (Invitrogen, PV3785) were diluted to make the final concentrations of 6 nM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent