BDBM518852 US11117902, Example 7

SMILES Oc1ccc2c(C(=O)c3ccc(OCCN4CC(CF)C4)cc3)c(cnc2c1)-c1cccc(c1F)C(F)(F)F

InChI Key InChIKey=HCRKEDZVGNVRNR-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 518852   

TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM518852(US11117902, Example 7)
Affinity DataKi:  1.55nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM518852(US11117902, Example 7)
Affinity DataKi:  8.55nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent