BDBM5189 (2E)-2-cyano-3-(naphthalen-1-yl)prop-2-enamide::naphthalene deriv. 23

SMILES NC(=O)C(=C\c1cccc2ccccc12)\C#N

InChI Key InChIKey=AVMHTBJNERNMNF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5189   

TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

LigandPNGBDBM5189((2E)-2-cyano-3-(naphthalen-1-yl)prop-2-enamide | n...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Hebrew University of Jerusalem

LigandPNGBDBM5189((2E)-2-cyano-3-(naphthalen-1-yl)prop-2-enamide | n...)
Affinity DataIC50: 1.00E+5nMAssay Description:The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2005
Entry Details Article
PubMed