BDBM519374 (4S,5R)-5-(3-bromo-5- fluorophenyl)-N- (isoquinolin-4- ylmethyl)-4-methyl-2- oxo-1,3-oxazolidine-3- carboxamide::US11141410, Example 25

SMILES C[C@H]1[C@H](OC(=O)N1C(=O)NCc1cncc2ccccc12)c1cc(F)cc(Br)c1

InChI Key InChIKey=OOWCBSFTILOIDO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 519374   

TargetN-acetylglucosamine-1-phosphotransferase subunits alpha/beta(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM519374((4S,5R)-5-(3-bromo-5- fluorophenyl)-N- (isoquinoli...)
Affinity DataIC50: 240nMAssay Description:The TarO biochemical enzymatic assay is a liquid chromatography-mass spectroscopy (LC-MS) based end point assay that measures C55-P-P-GlcNAc (LIPID I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent