BDBM519537 US11142520, Example 3

SMILES Fc1ccc(SC2C(=O)CC(NC2=O)(c2ccsc2)c2cccc(OCC3CCCC3)n2)c(Cl)c1

InChI Key InChIKey=IKUIRSQFPDRAQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 519537   

TargetL-lactate dehydrogenase A chain(Human)
Arctic Pharma

US Patent
LigandPNGBDBM519537(US11142520, Example 3)
Affinity DataIC50: 5.25E+3nMAssay Description:The inhibitory properties of the compounds were investigated using a coupled enzyme assay that links the lactate dehydrogenase (LDH) reaction to the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetL-lactate dehydrogenase B chain(Human)
Arctic Pharma

US Patent
LigandPNGBDBM519537(US11142520, Example 3)
Affinity DataIC50: 1.00E+5nMAssay Description:The inhibitory properties of the compounds were investigated using a coupled enzyme assay that links the lactate dehydrogenase (LDH) reaction to the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent