BDBM519562 US11142520, Example 15

SMILES CCOC(=O)OC1=C(Sc2cccc(Cl)c2Cl)C(=O)NC(C1)(c1ccsc1)c1ccc(cc1)N1CCOCC1

InChI Key InChIKey=OJXQGCMIURYYMQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 519562   

TargetL-lactate dehydrogenase A chain(Human)
Arctic Pharma

US Patent
LigandPNGBDBM519562(US11142520, Example 15)
Affinity DataIC50: 7.50E+4nMAssay Description:The inhibitory properties of the compounds were investigated using a coupled enzyme assay that links the lactate dehydrogenase (LDH) reaction to the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetL-lactate dehydrogenase B chain(Human)
Arctic Pharma

US Patent
LigandPNGBDBM519562(US11142520, Example 15)
Affinity DataIC50: 1.00E+5nMAssay Description:The inhibitory properties of the compounds were investigated using a coupled enzyme assay that links the lactate dehydrogenase (LDH) reaction to the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent