BDBM519599 US11142525, Example 15

SMILES CNCc1nc(cc2C(=O)N(Cc12)c1cccc(n1)-c1nncn1[C@@H](C)CC(F)(F)F)N1CCCC1

InChI Key InChIKey=BPZTXDXPWZYJON-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 519599   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Pfizer

US Patent

LigandBDBM519599(US11142525, Example 15)Copy SMILESCopy InChI

Affinity DataKi: <0.0700nMAssay Description:HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay (MSA). The reactions were conducted in 50 μL volumes in 96-well pl...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/4/2022
Entry Details
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