BDBM519635 US11142524, Compound 108::sodium 4-(2-((6-cyano-7-methyl-3H-

SMILES COc1cc(NC(=O)CSc2nc3c(C)c(ncc3[nH]2)C#N)ccc1OP([O-])([O-])=O

InChI Key InChIKey=RYJYHHFBKVYDRB-UHFFFAOYSA-L

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 519635   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
Stingray Therapeutics

US Patent
LigandPNGBDBM519635(sodium 4-(2-((6-cyano-7-methyl-3H- | US11142524, C...)
Affinity DataIC50: 2.05E+3nMAssay Description:Materials:Assay Buffer: 1 mM CaCl2, 0.2 mM ZnCl2, 50 mM Tris, pH 9.0 Substrate: 1.5 mM Thymidine 5′-monophosphate disodium salt hydrate (Sigma:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
Go to US Patent

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
Stingray Therapeutics

US Patent
LigandPNGBDBM519635(sodium 4-(2-((6-cyano-7-methyl-3H- | US11142524, C...)
Affinity DataIC50: 339nMAssay Description:MaterialsAssay Buffer: 1 mM CaCl2, 0.2 mM ZnCl2, 50 mM Tris, pH 9.0. Substrate: 100 μM Adenosine 5′-triphosphate disodium salt hydrate (Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
Go to US Patent