BDBM519713 US11142525, Example 114

SMILES CCn1cnnc1-c1cccc(n1)N1Cc2c(cc(nc2CNC)N2CCC[C@@H]2C)C1=O

InChI Key InChIKey=JSCXZLAMELFRIE-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 519713   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Pfizer

US Patent

LigandBDBM519713(US11142525, Example 114)Copy SMILESCopy InChI

Affinity DataKi:  0.120nMAssay Description:HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay (MSA). The reactions were conducted in 50 μL volumes in 96-well pl...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/4/2022
Entry Details
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