BDBM519791 US11142526, Example 5

SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2C(=O)c2cncnc2N2CCCC2)CC1)C(F)(F)F

InChI Key InChIKey=QLKRXBNLYYELMI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 519791   

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM519791(US11142526, Example 5)
Affinity DataIC50: 100nMAssay Description:Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM519791(US11142526, Example 5)
Affinity DataIC50: 100nMAssay Description:Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent