BDBM519821 1,1,1,3,3,3- Hexafluoropropan- 2-yl 1-((5-(4- methoxyphenyl) isoxazol-3- yl)methyl)-1,8- diazaspiro[4.5] decane-8- carboxylate::US11142526, Example 46

SMILES COc1ccc(cc1)-c1cc(CN2CCCC22CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)no1

InChI Key InChIKey=ORXCPRMMBTWTQG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 519821   

TargetMonoglyceride lipase(Mouse)
H. Lundbeck

US Patent
LigandPNGBDBM519821(1,1,1,3,3,3- Hexafluoropropan- 2-yl 1-((5-(4- meth...)
Affinity DataIC50: 100nMAssay Description:Inhibitors were administered to wild-type C57B1/6J by oral gavage in a vehicle of polyethylene glycol. Each animal was sacrificed 4 h following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent