BDBM519837 1,1,1,3,3,3- Hexafluoropropan- 2-yl 4-(((5- chlorobenzo[b] thiophen-2- yl)methyl)(methyl) amino)-4- methylpiperidine-1- carboxylate::US11142526, Example 62

SMILES CN(Cc1cc2cc(Cl)ccc2s1)C1(C)CCN(CC1)C(=O)OC(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=HREMSRUZPGKMFG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 519837   

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM519837(1,1,1,3,3,3- Hexafluoropropan- 2-yl 4-(((5- chloro...)
Affinity DataIC50: 100nMAssay Description:Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetMonoglyceride lipase(Mouse)
H. Lundbeck

US Patent
LigandPNGBDBM519837(1,1,1,3,3,3- Hexafluoropropan- 2-yl 4-(((5- chloro...)
Affinity DataIC50: 100nMAssay Description:Inhibitors were administered to wild-type C57B1/6J by oral gavage in a vehicle of polyethylene glycol. Each animal was sacrificed 4 h following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent