BDBM520018 (R)-methyl 4-(2-chloro-4-fluorophenyl)-6-(((S)-2-(4-(4-(morpholine-4-carbonyl) phenoxy)phenyl)-3-oxohexahydroimidazo[1,5-a]pyrazin-7(1H)-yl)methyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate::US11142527, Example 56

SMILES COC(=O)C1=C(CN2CCN3[C@H](CN(C3=O)c3ccc(Oc4ccc(cc4)C(=O)N4CCOCC4)cc3)C2)NC(=N[C@H]1c1ccc(F)cc1Cl)c1nccs1

InChI Key InChIKey=QAVKTQYPZGQAGA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 520018   

TargetLarge envelope protein(HBV-D)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM520018((R)-methyl 4-(2-chloro-4-fluorophenyl)-6-(((S)-2-(...)
Affinity DataEC50:  12.4nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent