BDBM520090 US11142535, Compound 4R

SMILES CN1CCC(CC1)N1CCN2[C@@H](COc3cc(Nc4nc(cn5ccnc45)-c4ccc5cn[nH]c5c4)ccc23)C1

InChI Key InChIKey=ZLWBQCJVMAGYTP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 520090   

TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520090(US11142535, Compound 4R)
Affinity DataIC50: 10nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent