BDBM520272 US11130750, Example 4

SMILES CC(C)[C@H]1c2ccc(F)cc2CC[C@@]1(CCN(C)CCCc1nc2c(C)ccc(C)c2[nH]1)OC(=O)NCCN(C)C

InChI Key InChIKey=AKLBSIJIPULMNR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 520272   

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandPNGBDBM520272(US11130750, Example 4)
Affinity DataIC50: 2.00E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandPNGBDBM520272(US11130750, Example 4)
Affinity DataIC50: 2.40E+4nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent